Uniqsis FlowSyn flow chemistry platform from Asynt

FlowSyn Continuous Flow Reactor

FlowSyn is a fully integrated, 2 channel benchtop continuous flow reactor that combines 2 high pressure pump channels and 2 reactor modules in a single compact unit.
Click the downloads area on this page to see a wide range of application notes for processes run on the FlowSyn…

FlowSyn’s high resolution user interface quickly guides you through the process of setting up and running flow chemistry reactions.

The unit can operate in either manual or fully automated modes, in the latter case ensuring that critical experiment parameters remain within defined limits, and can easily be reconfigured for a variety of experiments. Pump performance is constantly monitored and the user is alerted to potential flow rate variations.

All FlowSyns are fitted with the latest specification chemically resistant pump heads and injection valves, and can be specified with either PTFE, 316L stainless steel or Hastelloy C-276 flow paths for optimal chemical compatibility.

Choose FlowSyn for small scale single reactions (flow rate up to 20 ml/min). Add HotCoil(s) to increase reactor volume and throughput. For even higher throughput, choose FlowSyn Maxi.

Upgrade by adding a Multi-X fraction collector package in order to automatically run up to 10 sequential reactions, a Binary Pump Module to add additional pump channels, or a Polar Bear Plus Flow or Cold Coil cryogenic reactor module.

Leasing Options: It is now possible to lease or rent to buy a FlowSyn. There are real advantages to companies in leasing due to the way VAT is handled on the balance sheet. Terms are typically between 2 and 4 years. Longer term rental is also now possible and at the end of the lease or rental period there is the option to buy.

For more information or an online demonstration, please contact us.

Asynt – FlowSyn Application Note 17: Newman Kwart Rearrangement
FlowSyn application note 15: Bohlmann-Rahtz Pyridine Synthesis
FlowSyn Application Note 22: Flow nitration
FlowSyn Application Note 23 – Heterocyclic Synthesis: 20 Methylbenzimidazole
FlowSyn application note 24: 3-Hydroxy-4-quinolone
FlowSyn Application Note 25 – Mettalations Reactions using LiHMDS
Uniqsis Application Note 28 (Amidation with DABAL-Me3)
Publication 36: Continuous Bromination of Methanesulfones and Methansulfonates using KOBr
Publication 38: Continuous Flow alpha-Trifluoromethylation of Ketones under Metal-Free Visible Light Photoredox Catalysis
A flow procedure for the metalation of functionalized heterocycles
Publication 39: Flow Chemistry Platform for Low Temperature Reactions
Publication 40: Multistep Flow Synthesis of 5-Amino-2-aryl-2H-[1,2,3]-triazole-4-carbonitriles
RSC paper – efficient and selective hydrogen peroxide-mediated oxidation of sulfides in batch and segmented and continuous flow using a peroxometalate-based polymer immobilised ionic liquid phase catalyst

Space Saving – Compact Footprint, fully integrated system.
Safety – All pressurised parts are protected and isolated, no bare reactors. Active pressure monitoring system.
Time Saving – Short set up and reaction times.
Efficiency – Offers complete non attended operation. System will equilibrate, run reaction and clean automatically.
Optional full automation of reaction profiling
Wide range of coils from 1.8 mL to 60 mL in PTFE, stainless, Hastelloy, PFA, PTFE or silicone lined stainless tube
Highly chemically resistant system with 10 mL and 50 mL pump head options, we can pump BuLi, concentrated mineral acids and even greater on the Hastelloy and PTFE systems
Ability to run superheated reactions up to 260 °C and up to 1400 psi (100 bar)
Carry out reactions up to 260°C, 100 bar and 20 ml/min
100 ml/min, 200 bar and 300°C options available
Wide range of coil, chip and column reactor modules
Latest generation chemically inert high pressure pump heads
Durable coated stainless steel casework