Uniqsis Gas Addition Module (GAM II)
The Gas Addition Module II (GAM II) provides a safe and efficient means of performing gas-liquid reactions under continuous flow-through conditions and permits gas to be introduced “on demand” by diffusion through gas-permeable membrane tubing. This quickly creates a gas saturated solvent stream in typically less than 10 seconds.
The Gas Addition Module is compatible with a wide range of reactive gases (e.g. CO, CO2, H2, D2, ethene, ethyne, SO2) and organic solvents (e.g. THF, MeCN, MeOH, PrOH) and is designed to be connected in-line with any FlowSyn continuous flow reactor. Its primary purpose is to provide a solvent feed stream pre-saturated with gas, but it can also be used at ambient temperature as a reactor in its own right.
A length of gas-permeable DuPont AF2400 membrane tubing runs inside the full length of the coil reactor tubing containing the liquid phase in a ‘tube-in-tube’ arrangement. The gas and liquid phases cannot come into direct contact with each other at any point in the process. As the gas dissolved in the flowing liquid phase is consumed, more gas rapidly diffuses though the AF2400 tubing to replace it.
- Add to an existing FlowSyn or other flow reactor system
- Rapidly generate a continuous gas-saturated solvent stream
- Effortlessly perform gas-liquid reactions in flow
- Built-in features for safe gas management
Please contact us if you’d like further information or an online demonstration.
The GAM II can be heated and cooled just as with more conventional coil reactors and is available in 2 versions:
- To ensure the most efficient heat transfer, the standard outer reactor tubing can be manufactured from 316L stainless steel (UQ1095S).
- Alternatively, a thick-walled PTFE version (UQ1095) offers both improved chemical compatibility whilst allowing visualisation of the reaction mixture through the opaque tubing walls.
- Other options such as Hastelloy and PTFE-lined stainless steel are available upon request.
For maximum flexibility, the GAM II coil reactor is based upon a standard Uniqsis coil reactor mandrel. It is therefore compatible not only with FlowSyn, but also with the Polar Bear Plus Flow, the HotCoil and Standalone Cold Coil Mk II. Moreover, where longer residence times and/or higher throughputs are required, up to 2 of these reactors may be fitted in series to each of these instruments.
A key advantage of the GAM II is that, typically, the flowing liquid phase does not contain any undissolved gas bubbles, thereby ensuring greater stability, consistent flow rates and reproducible residence times.
To facilitate management of the gas input an optional stainless steel Gas Manifold (UQ1095M) fitted with a pressure gauge, additional in-line valving and safety burst valve is also available.
- DuPont AF2400 gas permeable inner membrane tubing
- Outer tubing is PTFE for optimal chemical compatibility
- Or choose 316L for optimal heat transfer
- Optional gas manifold available to help manage gas input
UK / Europe / Global Delivery
Developed in collaboration with our clients / Bespoke design service
Committed to developing sustainable & practical improvements for scientists worldwide
Martyn Fordham, MD
